Little Known Facts About ceesdekker.
Little Known Facts About ceesdekker.
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Applying solitary-molecule optical and AFM imaging and pressure-spectroscopy tactics, we seek out to unravel the mechanistic aspects of the composition and dynamics of chromosomes. Our investigation interests involve:
It was only from the 1990s while, when nanotechnology had State-of-the-art to some stage exactly where solitary molecules could be manipulated, that the 1st experimental devices commenced to appear.
[Laughs] ‘It was definitely a fantastic threat! At time, I was nicely mindful that it could go Improper and that I could become significantly less thriving, but I just overlooked that. Curiosity has often been my strongest driving power. And luckily everything labored out.’
2007, initially genuine-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence size of finishes of microtubules; and fixed the mechanism of biosensing with carbon nanotubes
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Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: speedy electron relay to redox enzymes and zeptomole protein-film voltammetry
MATLAB codes for info processing are available at . Julia codes employed for numerical simulation are available at .
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Understanding fundamental processes regulating the spatial and dynamic organisation of the DNA in live cells.
‘The fantastically delicate way during which components in nature functionality under no circumstances ceases to amaze me. If we resolve the puzzle of how life arrived into currently being, I assume that my amazement on the complexity of creation should have greater and with it my awe to the greatness from the Creator.’
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Many new phenomena ended up identified, and he and his research team established a number one place During this discipline of study. Dekker and his investigate group found out new physics of nanotubes and also explored the feasibility of molecular electronics. In 1998, they have been the very first to make a transistor depending on a single nanotube molecule.
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It had been a very exciting time, during which I obtained loads of help from Delft College of Technologies, wherever I had been a professor at the time, and I begun a number of collaborations with molecular biologists. That assisted me study a lot.’